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The process above is not as easy as it seems.What challenges may a scientist face when carrying out the following procedure?

Hey Amaan!
Thank you for your comment, I really appreciate your interest!
I agree with you. I work as an undergraduate student in a lab at UC Irvine, and I have run into numerous problems dealing with any types of cells, stem cells or not. A scientist faces many challenges because cells are constantly growing if and only if they are in a suitable environment. This means proper hormones, sufficient space to grow and cell-cell communication. There is also the possibility of contamination or bacterial infection, these will kill many cell, slow the growth of the entire colony and, in most cases, ruin the entire experiment. These are among the few problems that scientists face with all cells, this is why limb regeneration is not popular in humans yet. However, we’re getting there!
Thanks again Amaan, and keep reading!

-Amy

What about the genetic level?How can we inaugurate human limb regeneration alongside these challenges?

And how can we manufacture the bioengineered matrix in the above mentioned procedure?

If you click on the link “limb regeneration” that I posted in the blog (which was my source) you can read more about the bioengineered matrix. There are certain animal parts like cow collagen and shark elastin that go very well with the human immune system. These are the types of materials that they can use in the matrix so that our immune system doesn’t completely reject the stem cells. Additionally, the matrix is a tool used in order to embed the stem cells into the human body.

Hey Amaan We are sorry for the delay but we are having a huge spam issue, If you have any more questions feel free to email us. SJ (at) Scubasewj.com

Hey guys, thanx for the help!
Another thing that I thought about was, what if we extracted some stem cells from a foetus?And insert them into the amputated region of an arm?

And can you please tell me the procedure for cell extraction?

No problem Amaan. The thing with ESC (embryonic stem cells) is that there is great controversy with using them. I don’t know many details about that, but I do know that the ESC will NOT properly attach and grow in the amputated region. This is the function of the bioengineered matrix: to make the stem cells have a healthy environment filled with growth factors and to adapt to the amputated portion of the body. The body will reject the foreign stem cells, so the matrix creates an environment for the stem cells and amputated body to live in until the stem cells are ready to attach to the body. The matrix will eventually completely blend in with the body, leaving the stem cells and the body healthy and happily thriving.

So that’s it?! You mean, like, human limb regeneration is possible now?! Wow!

No, no, this is all still theory. Read the article that I linked to in the post. Think about this Amaan…how are they supposed to test this theory on human? Would you want to be the test subject for something like this? There are so many potential side effects like immune rejection, infection, errors in regeneration to the wrong parts, and these are just the things on the top of my head!! The main problem with this is that it involves so many different body systems. The nervous system to connect nerves from the body part to the brain and back. The skeletal system needs to lay down new bone to support the body part. The muscles, the skin, the hair…it never ends! That’s the biggest issue, making everything work together properly.